Description
The active ingredient in FORTEKOR is benazepril hydrochloride which is a second generation non-sulphydryl angiotensin converting enzyme (ACE) inhibitor. Following oral administration, benazepril hydrochloride is absorbed and converted by the liver to its active metabolite, benazeprilat.
Benazeprilat acts by inhibiting angiotensin converting enzyme (ACE). This enzyme is part of the renin-angiotensin cascade system and converts inactive Angiotensin I into biologically-active Angiotensin II, the hormone controlling vasoconstriction and release of aldosterone. Thus, ACE inhibitors prevent constriction of the blood vessels, thereby facilitating blood flow and reducing hypertension.